13 Anti-thymocyte globulin (ATG) vs. Basiliximab induction in renal transplant recipients: A long term outcome

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Relationship between post-transplant lymphoproliferative disorder and Anti-Thymocyte Globulin or Anti-Lymphocyte Globulin

 Abstract Background: Lymphoproliferative disorders are among the most serious and potentially fatal complications of chronic immunosuppression in kidney transplant recipients. The principle risk factors for development of PTLD are the degree of overall immunosuppression and the EBV serostatus of the recipient. In this study, the risk of PTLD in kidney transplant recipients who received Anti- L...

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Use of rabbit anti-thymocyte globulin for induction immunosuppression in high-risk kidney transplant recipients.

Kidney transplant remains the best type of renal replacement therapy in most patients with end-stage kidney disease, even in those with high immunologic risk. Immunosuppression in these patients is regarded as more complex, owing to the higher risk of both acute and chronic rejection. The advent of induction immunosuppression has resulted in a lower incidence of acute rejection and consequently...

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Comparison of Induction Therapy Using Anti-thymocyte Globulin and Using Basiliximab for Live Donor Kidney Transplant Recipients: a Single-center, Prospective, Cohort Study

Objective: Acute rejections (ARs) have a negative impact on long-term graft survival and are the major predictor of chronic rejection. Induction therapy is used to reduce AR and prevent delayed graft function (DGF). Anti-thymocyte globulin (ATG) and basiliximab are mainly used for this purpose. In this prospective, cohort study, we analyzed and compared the safety and efficacy of ATG and basili...

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Comparison of Basiliximab and Anti‐Thymocyte Globulin as Induction Therapy in Pediatric Heart Transplantation: A Survival Analysis

BACKGROUND Basiliximab and anti-thymocyte globulin are widely used drugs for induction therapy after pediatric heart transplantation. The aim of this study was to determine whether any differences could be observed between basiliximab and anti-thymocyte globulin, with respect to long-term mortality, in a population of pediatric cardiac transplant recipients. METHODS AND RESULTS An analysis of...

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Impaired glucose homeostasis in renal transplant recipients receiving basiliximab.

BACKGROUND The pathogenesis of new onset diabetes after transplantation (NODAT) is multifactorial. Suppression of regulatory T lymphocytes may have a negative impact on pancreatic beta-cells. Induction with basiliximab affects regulatory T-cell function and may therefore, theoretically, also affect glucose homeostasis in renal transplant recipients. METHODS All kidney recipients > or =50 year...

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ژورنال

عنوان ژورنال: Indian Journal of Transplantation

سال: 2011

ISSN: 2212-0017

DOI: 10.1016/s2212-0017(11)60017-8